Implementing an early intensive care bundle with blood pressure reduction improved outcomes for patients with acute intracerebral hemorrhage, according to new research. The study was conducted at hospitals in 10 countries: Brazil, China, India, Mexico, Nigeria, Pakistan, Peru, Sri Lanka, Vietnam, and Chile. The care bundle focused on the early intensive reduction of systolic blood pressure, strict glucose control, anti-pyrexia treatment, and rapid reversal of warfarin-related anticoagulation within 1 hour of treatment. The modified intention-to-treat population included 7,036 patients with a mean age of 62 years : 3,221 in the care bundle group and 3,815 in the usual care group. In all, 90.4% of patients had a blood pressure of 140 mm Hg or higher, with an overall mean systolic blood pressure of 174.5 mm Hg; 36% of patients had elevated blood glucose; 1.7% had an elevated body temperature; and 1.2% had a higher international normalized ratio at presentation. The median volume of hemorrhage was 15.0 mL, and 29.8% had intraventricular hemorrhage. Patients in the care bundle group were less likely to have a poor functional outcome compared with those in the usual care group (common odds ratio 0·86; p=0·015). Additionally, they had fewer serious adverse events, at a rate of 16.0% vs. 20.1% in the usual care group. “Implementation of a care bundle protocol for intensive blood pressure lowering and other management algorithms for physiological control within several hours of the onset of symptoms resulted in improved functional outcome for patients with acute intracerebral hemorrhage,” the researchers concluded, suggesting that hospitals may want to adopt this approach for active management of this condition.