Neurocritical Care Society

Literature Watch

Endovascular Thrombectomy for Large Ischemic Stroke Across Ischemic Injury and Penumbra Profiles

Written By: NCS Staff

An exploratory analysis of SELECT2, a randomized clinical trial of patients with acute ischemic stroke and large cores, shows that endovascular...

Literature Watch

Time to Treatment With Intravenous Thrombolysis Before Thrombectomy and Functional Outcomes in Acute Ischemic Stroke

Written By: NCS Staff

An exploratory analysis of SELECT2, a randomized clinical trial of patients with acute ischemic stroke and large cores, shows that endovascular...

Literature Watch

Critical Care Management of Patients After Cardiac Arrest: A Scientific Statement From the American Heart Association and Neurocritical Care Society

Written By: NCS Staff

The American Heart Association Emergency Cardiovascular Care Committee and the Neurocritical Care Society convened an expert consensus panel and...

Literature Watch

In-Hospital Neurologic Complications, Neuromonitoring, and Long-Term Neurologic Outcomes in Patients With Sepsis: A Systematic Review and Meta-Analysis

Written By: NCS Staff

A recent systematic review and meta-analysis evaluated neurocognitive outcomes and the use of neuromonitoring tools for hospitalized sepsis...

Literature Watch

Intensive vs Conventional Blood Pressure Lowering After Endovascular Thrombectomy in Acute Ischemic Stroke and Blood Pressure Management After Endovascular Therapy for Acute Ischemic Stroke

Written By: NCS Staff

Two new studies focus on blood pressure (BP) management after endovascular therapy for acute ischemic stroke. In the OPTIMAL-BP randomized...

Literature Watch

The Neurological Pupil Index for Outcome Prognostication in People With Acute Brain Injury (Orange): A Prospective, Observational, Multicentre Cohort Study

Written By: NCS Staff

A new study demonstrates the prognostic value of the Neurological Pupil index (NPi) for monitoring disease progression and predicting outcomes for...

Literature Watch

Effects of Hypothermia vs Normothermia on Societal Participation and Cognitive Function at 6 Months in Survivors After Out-Of-Hospital Cardiac Arrest

Written By: NCS Staff

New research shows that for survivors of out-of-hospital cardiac arrest (OHCA), targeted hypothermia did not improve functional outcome with a...

Literature Watch

Symptomatic Intracranial Hemorrhage With Tenecteplase vs Alteplase in Patients With Acute Ischemic Stroke

Written By: NCS Staff

Stroke thrombolysis with tenecteplase was associated with a lower risk of symptomatic intracranial hemorrhage (sICH) compared with treatment with...

Literature Watch

The Third Intensive Care Bundle With Blood Pressure Reduction in Acute Cerebral Haemorrhage Trial (INTERACT3): An International, Stepped Wedge Cluster Randomised Controlled Trial

Written By: NCS Staff

Implementing an early intensive care bundle with blood pressure reduction improved outcomes for patients with acute intracerebral hemorrhage,...

Literature Watch

Early Versus Later Anticoagulation For Stroke With Atrial Fibrillation

Written By: NCS Staff

A recent study investigated the safety and efficacy of early initiation of direct oral anticoagulants (DOACs) compared with later, guideline-based...

Literature Watch

Reversibility of Diffusion-Weighted Imaging Lesions in Patients With Ischemic Stroke in the WAKE-UP Trial

Written By: NCS Staff

A retrospective analysis of the Efficacy and Safety of Magnetic Resonance Imaging-Based Thrombolysis in Wake-Up Stroke (WAKE-UP) trial identified...

Literature Watch

Decompressive Craniectomy Versus Craniotomy for Acute Subdural Hematoma

Written By: NCS Staff

For patients with acute ischemic stroke within 4.5 hours of symptom onset, tenecteplase is non-inferior to alteplase, according to new research....

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Literature Watch

Alteplase for Posterior Circulation Ischemic Stroke at 4.5 to 24 Hours

Written By: NCS Staff

Findings from the EXPECTS randomized clinical trial make a case for extending the therapeutic window for I.V. thrombolysis following posterior...

Literature Watch

Intravenous Thrombolysis Before Endovascular Treatment Versus Endovascular Treatment Alone for Patients With Large Vessel Occlusion and Carotid Tandem Lesions: Individual Participant Data Meta-Analys

Written By: NCS Staff

In patients with carotid tandem lesions, adding intravenous thrombolysis to endovascular treatment had no significant impact on bleeding or...

Literature Watch

Optimal Delay Time to Initiate Anticoagulation After Ischemic Stroke in Atrial Fibrillation

Written By: NCS Staff

A Phase II clinical trial sought to determine whether there is an ideal delay time to start treatment with a direct oral anticoagulant (DOAC)...