The American Heart Association Emergency Cardiovascular Care Committee and the Neurocritical Care Society convened an expert consensus panel and conference to identify knowledge gaps and provide additional guidance for the critical care management of patients after cardiac arrest. Specifically, they examined acute and critical care management of adult cardiac arrest survivors resuscitated from in-hospital and out-of-hospital cardiac arrest. The panel – which included two dozen practitioners in medicine, nursing, pharmacy, and respiratory therapy – identified topics including neurological, cardiac, pulmonary, hematological, infectious, gastrointestinal, endocrine, and general critical care management. Statements were included if there was at least 80% agreement from panelists. The experts also noted areas in which no consensus was reached and directions for research going forward.