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Intravenous Alteplase for Stroke With Unknown Time of Onset Guided by Advanced Imaging: Systematic Review and Meta-Analysis of Individual Patient Data

The Lancet (11/14/20) Vol. 396, No. 10262, P. 1574 doi: 10.1016/S0140-6736(20)32163-2 Thomalla, Götz; Boutitie, Florent; Ma, Henry; et al. https://www.thelancet.com/journals/lancet/article/PIIS0140-6736(20)32163-2/fulltext Although stroke patients with unknown time of onset have...


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The Impact of Delirium on Withdrawal of Life-Sustaining Treatment After Intracerebral Hemorrhage

Neurology (11/17/20) Vol. 95, No. 20 doi: 10.1212/WNL.0000000000010738 Reznik, Michael E.; Moody, Scott; Murray, Kayleigh; et al. https://n.neurology.org/content/95/20/e2727 Researchers report an association between delirium and withdrawal of life-sustaining treatment (WLST) after...


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Translational Research in Neurocritical Care

By Yama Akbari MD, PhD, and Michael L. James MD, FAHA Acknowledgement: ROSC Currents Taskforce (Shraddha Mainali, MD; Jennifer Kim, MD, PhD; Ruchi Jha, MD; Tom Lawson, CNP; Minjee Kim, MD; Cassia Righy, MD, PhD; Caitlin Brown, PharmD) Translational research “moves [work] in a...


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NEWS: Intense Lowering of SBP in ICH Patients With Excessively High SBP: Are We Worsening Neurological Outcome?

Qureshi AI, Huang W, Lobanova I, et al. Outcomes of Intensive Systolic Blood Pressure Reduction in Patients With Intracerebral Hemorrhage and Excessively High Initial Systolic Blood Pressure: Post Hoc Analysis of a Randomized Clinical Trial [published online ahead of print, 2020 Sep 8]. JAMA...


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Frequent Neurologic Manifestations and Encephalopathy‐Associated Morbidity in COVID‐19 Patients

Annals of Clinical and Translational Neurology (10/05/20) doi: 10.1002/acn3.51210 Liotta, Eric M.; Batra, Ayush; Clark, Jeffrey R.; et al. https://onlinelibrary.wiley.com/doi/full/10.1002/acn3.51210 Most hospitalized COVID-19 patients experienced neurologic symptoms at some point during...


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Symptomatic Intracranial Hemorrhage After Mechanical Thrombectomy in Chinese Ischemic Stroke Patients

Stroke (09/20) Vol. 51, No. 9 doi: 10.1161/STROKEAHA.120.030173 Zhang, Xiaohao; Xie, Yi; Wang, Huaiming; et al. https://www.ahajournals.org/doi/10.1161/STROKEAHA.120.030173 Researchers sought to create a risk model able to predict symptomatic intracranial hemorrhage (sICH) in Chinese...


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NEWS: Aspirin Plus Ticagrelor Is Superior to Aspirin Monotherapy for Reducing Recurrent Stroke and Death After Mild-moderate Ischemic Stroke or TIA

Claiborne Johnston, Pierre Amarenco, et al. for the THALES investigators.Ticagrelor and Aspirin or Aspirin Alone in Acute Ischemic Stroke or TIA. N Engl J Med 2020;383:207-17. DOI: 10.1056/NEJMoa1916870 Reviewed by Sanjeev Sivakumar,MD Read the article .* *You will need to log...


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NEWS: Association of NIH Stroke Scale and Collateral Circulation with Outcomes after Endovascular Therapy for Basilar Artery Occlusion

Kwak HS, Park JS. Mechanical Thrombectomy in Basilar Artery Occlusion: Clinical Outcomes Related to Posterior Circulation Collateral Score. Stroke . 2020;51(7):2045-2050. doi:10.1161/STROKEAHA.120.029861 Reviewed by Shannon Hextrum, MD Read the article .* *You will need to log in...


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Considerations for Reduction of Risk of Perioperative Stroke in Adult Patients Undergoing Cardiac and Thoracic Aortic Operations: A Scientific Statement From the American Heart Association

Circulation (08/26/20) doi: 10.1161/CIR.0000000000000885 Gaudino, Mario; Benesch, Curtis; Bakaeen, Faisal; et al. https://www.ahajournals.org/doi/10.1161/CIR.0000000000000885 A scientific statement from the American Heart Association (AHA) recommends specific preoperative,...


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Assessment of Brain Injury Using Portable, Low-Field Magnetic Resonance Imaging at the Bedside of Critically Ill Patients

JAMA Neurology (09/08/20) doi: 10.1001/jamaneurol.2020.3263 Sheth, Kevin N.; Mazurek, Mercy H.; Yuen, Matthew M.; et al. https://jamanetwork.com/journals/jamaneurology/fullarticle/2769858 A recent study demonstrates the successful use of low-field, portable magnetic resonance imaging ...