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NEWS: Endovascular Thrombectomy Alone Is Non-inferior to Thrombectomy With Alteplase: Results of the DIRECT-MT Study

Yang P, Zhang Y, Zhang L, et al. Endovascular Thrombectomy with or without Intravenous Alteplase in Acute Stroke. N Engl J Med . 2020 May 21;382(21):1981-93. Reviewed by Wazim Mohamed, MD Read the article .* *You will need to log in to US National Library of Medicine National...


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NEWS: Degree of Blood Pressure Reduction in ICH Predicts Poor Outcome

Divani A, Liu X, Petersen A, et al. The magnitude of blood pressure reduction predicts poor in-hospital outcome in acute intracerebral hemorrhage. Neurocrit Care (2020). Reviewed by Kyle Hobbs, MD Read the article . Summary While elevated systolic blood pressure ...


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NEWS: Determining Optimum ICP Threshold for Patients with Acute Neurological Injury

Hawryluk GWJ, Nielson JL, Huie JR, et al. Analysis of Normal High-Frequency Intracranial Pressure Values and Treatment Threshold in Neurocritical Care Patients: Insights into Normal Values and a Potential Treatment Threshold. JAMA Neurol. Published online June 15, 2020. doi:10.1001/jamaneurol...


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Pandemic Guidance for Stroke Centers Aiding COVID-19 Treatment Teams

Stroke (08/20) Vol. 51, No. 8: 2587–2592 doi: 10.1161/STROKEAHA.120.030749 Wira, Charles R.; Goyal, Mayank; Southerland, Andrew M; et al. https://www.ahajournals.org/doi/10.1161/STROKEAHA.120.030749 The Stroke Nursing Science Subcommittee of the AHA/ASA Cardiovascular and Stroke Nursing...


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Determination of Brain Death/Death by Neurologic Criteria: The World Brain Death Project

Journal of the American Medical Association (08/03/20) doi: 10.1001/jama.2020.11586 Greer, David M.; Shemie, Sam D.; Lewis, Ariane; et al. https://jamanetwork.com/journals/jama/fullarticle/2769149 A new report provides guidelines for determining brain death in children and adults. The...


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Implementation of a Prehospital Stroke Triage System Using Symptom Severity and Teleconsultation in the Stockholm Stroke Triage Study

JAMA Neurology (06/01/20) doi: 10.1001/jamaneurol.2020.0319 Mazya, Michael V.; Berglund, Annika; Ahmed, Niaz; et al https://jamanetwork.com/journals/jamaneurology/article-abstract/2763539 A new prehospital stroke triage system resulted in much shorter delivery times for endovascular...


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Risk of Ischemic Stroke in Patients With Coronavirus Disease 2019 (COVID-19) vs Patients With Influenza

JAMA Neurology (07/02/20) doi: 10.1001/jamaneurol.2020.2730 Merkler, Alexander E.; Parikh, Neal S.; Saad Mir; et al https://jamanetwork.com/journals/jamaneurology/fullarticle/2768098 Patients with COVID-19 may be at increased risk for risk for stroke compared with patients with influenza,...


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Analysis of Normal High-Frequency Intracranial Pressure Values and Treatment Threshold in Neurocritical Care Patients

JAMA Neurology (06/15/20) doi: 10.1001/jamaneurol.2020.1310 Hawryluk, Gregory W. J.; Jessica L. Nielson; Huie, J. Russell; et al. https://jamanetwork.com/journals/jamaneurology/article-abstract/2767085 To better understand the association between intracranial pressure (ICP) and outcome,...


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Impact of COVID-19 Pandemic on Critical Care Transfers for ST-Elevation Myocardial Infarction, Stroke, and Aortic Emergencies

Circulation: Cardiovascular Quality and Outcomes (06/11/20) doi: 10.1161/CIRCOUTCOMES.120.006938 Khot, Umesh N.; Reimer, Andrew P.; Brown, Abigail; et al. https://www.ahajournals.org/doi/10.1161/CIRCOUTCOMES.120.006938 New research shows a reduction in emergency transfers for serious...


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Collateral Effect of COVID-19 on Stroke Evaluation in the United States

New England Journal of Medicine (05/08/20) doi: 10.1056/NEJMc2014816 Kansagra, Akash P.; Goyal, Manu S.; Hamilton, Scott; et al. https://www.nejm.org/doi/full/10.1056/NEJMc2014816 The number of patients who underwent imaging for the evaluation of stroke decreased from a prepandemic...