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Frequent Neurologic Manifestations and Encephalopathy‐Associated Morbidity in COVID‐19 Patients

By Currents Editor posted 11-02-2020 11:51


Annals of Clinical and Translational Neurology (10/05/20) doi: 10.1002/acn3.51210

Liotta, Eric M.; Batra, Ayush; Clark, Jeffrey R.; et al.

Most hospitalized COVID-19 patients experienced neurologic symptoms at some point during the course of the disease, according to new research. The retrospective study—conducted within a hospital network in Chicago—identified neurologic manifestations at COVID-19 onset among 42.2% (215) of 509 patients, at hospitalization in 62.7% (319), and at any time during the disease in 82.3% (419). The most frequent neurologic symptoms were myalgias, headaches, encephalopathy, dizziness, dysgeusia, and anosmia. Severe COVID-19 infection and younger age were independent risk factors for developing any neurologic symptom. The researchers report that 71.1% of the patients had a favorable functional outcome at discharge. However, for encephalopathy patients, there were lower functional outcomes and an increase risk of death within 30 days of hospitalization.



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