A study of more than 1,500 patients with aneurysmal subarachnoid hemorrhage (aSAH) found no association between internal jugular central venous catheter (IJ CVC) placement and increased intracranial pressure (ICP), contrary to classic teaching. Jugular access for CVC has long been avoided due to concerns about risks to jugular venous outflow and raising cerebral blood volume in patients who also have ICP problems. The single-center, retrospective study - conducted from 2012 through 2020 - assigned patients by the access site of the first CVC placed, with additional study for those with an external ventricular drain (EVD).  Of the 1,577 patients admitted during the study period with CVC access, 56.2% had subclavian (SC) access, 23.1% had IJ access, 16.0% had peripheral inserted central catheters (PICCs), and 4.6% had femoral access. SC was associated with traumatic pneumothorax. Between sites, there was no difference in catheter-associated infections; however, catheter-associated deep venous thrombosis was most common with femoral access. For the 1,220 patients with an EVD, there were 351,462 ICP measurements. The researchers found ICP measurements were similar between groups during the initial 24 hours postinsertion and over the next 10 days. “Together, these data support the safety and at least noninferiority of ultrasound-guided IJ venous catheterization in patients with aSAH,” the researchers conclude.